Week 14 discussion. Word document attached with questions.
From the Professor:
The HPAT axis is affected by any stressor: environmental, physiological, neurological- even a stressful thought upregulated the HPAT axis.
Chronic stress may produce subclinical hypothyroidism. Chronic stress decreases the effectiveness of glucocorticoid receptors-rendering them glucocorticoid resistant (similar to insulin resistance) –> upregulating inflammation. Increased inflammation –> ^ Reactive Oxidative Species–> less ATP production in mitochondria. Wonder why patients/clients who have sustained stress also complain of myalgia/arthralgia as well as fatigue??? Chronic stress also results in dysbiosis–> leading to decreased production of healthy neurotransmitters serotonin and dopamine–> anxiety /depression. This anxiety/depression then leads to more stress–> more dysbiosis–> less healthy neurotransmitters–> increased anxiety/depression–> and now a downward spiral. Prolonged stress places the body in fight/flight and more glucose is released into the blood stream to travel to the muscles so the patient/client can “run away from the saber tooth tiger”–> leading to hyperglycemia. Prolonged hyperglycemia–> ^^ inflammation.

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From the Professor: appeared first on Excel Essay Helpers.